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Biology 350: Cell Biology Lecture
Note to students taking the course: all the course material is available on Desire2Learn
In the Cell Biology course, we will attempt to gain an understanding ofthe structure and function of eukaryotic cells. Recent advances in molecular biology and biochemistry have allowed the study of cell biology to focus on the molecular mechanisms by which organelles and macromolecules interact to perform specific functions within and around each cell. This course aims to give an overview of the major cellular elements and processes, and how these play crucial roles in tissue, organ, and organismal structure and function.
In addition to requisite topics such as biosynthesis and bioenergetics,the course focuses on three general areas of cellular function: protein synthesis and traffic, cytoskeletal structure and function, and cell signaling pathways.
Upon completion of this course, students will be expected to:
- recognize the structure and function of major eukarotic organelles and explain how macromolecules are trafficked within and between specific organelles.
- describe the steps involved in energy production and consumption, and how these pertain to organismal function.
- identify the components of the cytoskeleton andextracellular matrix, and elucidate how they affect cell structure, function, metabolism, and division.
- understand how cells receive and process signals, and how these signals affect cell morphology and physiology.
- understand important applications of cell biology and apply your basic knowledge of cell biology to novel biological and medical problems
Students who take this course should have successfully completed Biology 142 and 142 (lecture and lab). It is recommended (but not required) that students take a 200- level laboratory course prior totaking Biology 350. Students must concurrently enroll in the lecture and laboratory portions of the course.
Course introduction and Cell Theory
Review of Cellular Chemistry
Proteins: structure and function
Protein Synthesis and Processing
Cell surface: Structure and Transport
Nuclear Structures, Metabolism and Transport
Mitochondria, Plastids, & Bioenergetics
Golgi and vesicular transport
Lysosomes, Endocytosis and Exocytosis
Cytoskeleton : Microtubules and Motors
Cytoplasm, Micro- & Intermediate Filaments
Cytoskeleton: Actin, Myosin, and Cell Motility
Integration Lecture: Putting it all together
Cell Signaling: Ligands and Receptors
Second Messenger Signaling I
Second Messenger Signaling II
Cell Signaling: Receptor Kinases and Phosphatases
Cell Signaling: Receptor Kinases and Phosphatases II
Cell Signaling: Extracellular Matrix and Long Distance Communication
Cell Signaling: Extracellular Matrix and Long Distance Communication II
Cell Growth, Senescence, and Death
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