Biology 350: Cell Biology Lecture

Note to students taking the course: all the course material is available on Angel

Overview:
In the Cell Biology course, we will attempt to gain an understanding ofthe structure and function of eukaryotic cells.  Recent advances in molecular biology and biochemistry have allowed the study of cell biology to focus on the molecular mechanisms by which organelles and macromolecules interact to perform specific functions within and around each cell.  This course aims to give an overview of the major cellular elements and processes, and how these play crucial roles in tissue, organ, and organismal structure and function.
In addition to requisite topics such as biosynthesis and bioenergetics,the course focuses on three general areas of cellular function: protein synthesis and traffic, cytoskeletal structure and function, and cell signaling pathways.

Course Objectives:

Upon completion of this course, students will be expected to:


Prerequisites:
Students who take this course should have successfully completed Biology 142 and 142 (lecture and lab).  It is recommended (but not required) that students take a 200- level laboratory course prior totaking Biology 350.  Students must concurrently enroll in the lecture and laboratory portions of the course.

Sample Syllabus::

1 Course introduction and Cell Theory
2 Review of Cellular Chemistry
3 Proteins: structure and function
4 Nuclear Structures, Metabolism and Transport
5 Protein Synthesis and Processing
6 Golgi and vesicular transport
7 Lysosomes, Endocytosis and Exocytosis
EXAM I
8 Cytoskeleton : Microtubules and Motors
9 Cytoplasm, Micro- & Intermediate Filaments
10 Cytoskeleton: Actin, Myosin, and Cell Motility
11 Integration Lecture: Putting it all together
12 Carbohydrate Biosynthesis
13 Mitochondria & Bioenergetics
EXAM II
14 Cell surface: Structure and Transport
15 Cell Signaling: Ligands and Receptors
16 Second Messenger Signaling I
17 Second Messenger Signaling II
18 Cell Signaling: Receptor Kinases and Phosphatases
19 Cell Signaling: Receptor Kinases and Phosphatases II
EXAM III
20 Cell Signaling: Extracellular Matrix and Long Distance Communication
21 Cell Signaling: Extracellular Matrix and Long Distance Communication II
22 Cell Cycle
23 Cell Growth, Senescence, and Death
24 Cancer
EXAM IV